Phenolic compounds from allium schoenoprasum, tragopogon pratensis and rumex acetosa and their antiproliferative effects

Kuceková, Zdenka; Mlček, Jiří; Humpolíček, Petr; Rop, Otakar; Valášek, Pavel; Sáha, Petr

dc.title	Phenolic compounds from allium schoenoprasum, tragopogon pratensis and rumex acetosa and their antiproliferative effects	en
dc.contributor.author	Kuceková, Zdenka
dc.contributor.author	Mlček, Jiří
dc.contributor.author	Humpolíček, Petr
dc.contributor.author	Rop, Otakar
dc.contributor.author	Valášek, Pavel
dc.contributor.author	Sáha, Petr
dc.relation.ispartof	Molecules
dc.identifier.issn	1420-3049 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued	2011
utb.relation.volume	16
utb.relation.issue	11
dc.citation.spage	9207
dc.citation.epage	9217
dc.type	article
dc.language.iso	en
dc.identifier.doi	10.3390/molecules16119207
dc.relation.uri	http://www.mdpi.com/1420-3049/16/11/9207/
dc.subject	allium schoenoprasum	en
dc.subject	HaCaT	en
dc.subject	phenolic compounds	en
dc.subject	proliferation	en
dc.subject	rumex acetosa	en
dc.subject	tragopogon pratensis	en
dc.description.abstract	Experimental studies have shown that phenolic compounds have antiproliferative and tumour arresting effects. The aim of this original study was to investigate the content of phenolic compounds (PhC) in flowers of Allium schoenoprasum (chive), Tragopogon pratensis (meadow salsify) and Rumex acetosa (common sorrel) and their effect on proliferation of HaCaT cells. Antiproliferative effects were evaluated in vitro using the following concentrations of phenolic compounds in cultivation medium: 100, 75, 50 and 25 ÎĽg/mL. Phenolic composition was also determined by HPLC. The results indicate that even low concentrations of these flowers' phenolic compounds inhibited cell proliferation significantly and the possible use of the studied herb's flowers as sources of active phenolic compounds for human nutrition. Â© 2011 by the authors; licensee MDPI, Basel, Switzerland.	en
utb.faculty	Faculty of Technology
utb.faculty	University Institute
dc.identifier.uri	http://hdl.handle.net/10563/1002634
utb.identifier.rivid	RIV/70883521:28110/11:43865483!RIV12-MSM-28110___
utb.identifier.rivid	RIV/70883521:28610/11:43865483!RIV12-MSM-28610___
utb.identifier.obdid	43865494
utb.identifier.scopus	2-s2.0-82255164524
utb.identifier.wok	000297697200024
utb.identifier.coden	MOLEF
utb.source	j-scopus
dc.date.accessioned	2012-02-10T13:15:20Z
dc.date.available	2012-02-10T13:15:20Z
dc.rights	Attribution-NonCommercial-NoDerivs 3.0 Unported
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/3.0/
dc.rights.access	openAccess
utb.ou	Centre of Polymer Systems
utb.contributor.internalauthor	Kuceková, Zdenka
utb.contributor.internalauthor	Mlček, Jiří
utb.contributor.internalauthor	Humpolíček, Petr
utb.contributor.internalauthor	Rop, Otakar
utb.contributor.internalauthor	Valášek, Pavel
utb.contributor.internalauthor	Sáha, Petr
utb.fulltext.affiliation	Zdenka Kucekova 1, Jiri Mlcek 2, Petr Humpolicek 1,3,, Otakar Rop 2, Pavel Valasek 3 and Petr Saha 3 1 Polymer Centre, Faculty of Technology, Tomas Bata University at Zlin, T.G.M. sq. 275, 762 72, Zlin, Czech Republic; E-Mail: kucekova@ft.utb.cz (Z.K.) 2 Department of Food Technology and Microbiology, Faculty of Technology, Tomas Bata University at Zlin, T.G.M. sq. 275, 762 72 Zlin, Czech Republic; E-Mails: mlcek@ft.utb.cz (J.M.); rop@ft.utb.cz (O.R.) 3 Centre for Polymer Systems, Polymer Centre, Tomas Bata University at Zlin, T.G.M. sq. 5555, 760 05 Zlin, Czech Republic; E-Mails: valasek@ft.utb.cz (P.V.); saha@utb.cz (P.S.) Author to whom correspondence should be addressed; E-Mail: humpolicek@uni.utb.cz; Tel.: +420-576-038-035; Fax: +420-576-031-444.
utb.fulltext.dates	Received: 29 August 2011 in revised form: 21 October 2011 Accepted: 26 October 2011 Published: 3 November 2011
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utb.fulltext.sponsorship	This article was created with the support of Operational Program Research and Development for Innovations co-funded by the European Regional Development Fund (ERDF) and the national budget of the Czech Republic, within the framework of the Centre of Polymer Systems project (reg. number: CZ.1.05/2.1.00/03.0111). The work was also supported by a research project of the Ministry of Education, Youth and Sports of the Czech Republic (MSM 7088352101). Author Z. Kuceková thanks the internal grant of TBU at Zlin No. IGA/20/FT/11/D funded from the specific university research resources for support
utb.fulltext.projects	CZ.1.05/2.1.00/03.0111
utb.fulltext.projects	MSM 7088352101
utb.fulltext.projects	IGA/20/FT/11/D