Surface energy analysis (SEA) study of hyaluronan powders

Abstract

Results of inverse gas chromatography adsorption/desorption experiments of selected probes on sodium hyaluronate powder material are presented. It was found that a dominating was a dispersive surface energy part thus indicating low polarity character of the studied HA powder. For 0% coverage 30mJ/m2 total surface energy was found. There was found a relatively high inhomogeneity of the surface structure of the studied polymer powder. A total surface energy distribution was ranging from 10 to 34mJ/m2 with maximum at 18.5mJ/m2. It was similarly as in the previous case of surface energy profile controlled by dispersive part. By measuring free energy profiles dependencies for selected probe molecules of different polarity there was found approximately seven-fold higher energy content (15kJ/mol) in comparison to dichloromethane (2kJ/mol). There were determined work of cohesion and work of adhesion (water) on HA surface. © 2013 Elsevier B.V.