Kontaktujte nás | Jazyk: čeština English
Název: | Prognostic influence of internal mammary node drainage in patients with early-stage breast cancer | ||||||||||
Autor: | Lukešová, Lucie; Vrána, David; Švach, Ivan; Zlámalová, Nora; Gatěk, Jiří; Vlachová, Zuzana; Matzenauer, Marcel; Koranda, Pavel; Hrůzová, Klára; Tichý, Tomáš; Melichar, Bohuslav | ||||||||||
Typ dokumentu: | Recenzovaný odborný článek (English) | ||||||||||
Zdrojový dok.: | Anticancer Research. 2016, vol. 36, issue 12, p. 6641-6646 | ||||||||||
ISSN: | 0250-7005 (Sherpa/RoMEO, JCR) | ||||||||||
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DOI: | https://doi.org/10.21873/anticanres.11272 | ||||||||||
Abstrakt: | Background: The management of internal mammary nodes (IMNs) during multidisciplinary treatment of breast cancer has been debated for the last four decades without unequivocal conclusion. Patients and Methods: We retrospectively reviewed patients with breast cancer who underwent sentinel lymph node biopsy at our center from 2008 until 2012. IMN drainage was assessed as a potential risk factor for local and distant disease recurrence. Results: We identified 712 patients, with incidence of drainage to IMNs of 18.4%. No detrimental effect of the pattern of drainage to IMNs was found after a median follow-up of 58 months. A similar outcome was observed when drainage to IMNs was evaluated as a risk factor for patient survival. The potential risk factors for drainage to IMNs during sentinel lymph node biopsy were younger age (p=0.002) and tumor location in lower-outer, lower-inner, and upper-inner versus upper-outer quadrant (p<0.0001). Conclusion: The drainage to IMNs is unlikely to have a detrimental effect on patient outcome. | ||||||||||
Plný text: | http://ar.iiarjournals.org/content/36/12/6641.abstract | ||||||||||
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