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dc.title | Effect of plasma treatment on the release kinetics of a chemotherapy drug from biodegradable polyester films and polyester urethane films | en |
dc.contributor.author | Stloukal, Petr | |
dc.contributor.author | Novák, Igor | |
dc.contributor.author | Mičušík, Matej | |
dc.contributor.author | Procházka, Michal | |
dc.contributor.author | Kucharczyk, Pavel | |
dc.contributor.author | Chodák, Ivan | |
dc.contributor.author | Lehocký, Marián | |
dc.contributor.author | Sedlařík, Vladimír | |
dc.relation.ispartof | International Journal of Polymeric Materials and Polymeric Biomaterials | |
dc.identifier.issn | 0091-4037 Scopus Sources, Sherpa/RoMEO, JCR | |
dc.date.issued | 2018 | |
utb.relation.volume | 67 | |
utb.relation.issue | 3 | |
dc.citation.spage | 161 | |
dc.citation.epage | 173 | |
dc.type | article | |
dc.language.iso | en | |
dc.publisher | Taylor and Francis Inc. | |
dc.identifier.doi | 10.1080/00914037.2017.1309543 | |
dc.relation.uri | https://www.tandfonline.com/doi/full/10.1080/00914037.2017.1309543 | |
dc.subject | Biodegradable materials | en |
dc.subject | capacitively coupled radio frequency plasma | en |
dc.subject | control release | en |
dc.subject | diffuse coplanar surface barrier discharge | en |
dc.subject | plasma treatments | en |
dc.description.abstract | Investigation was made into the effect of plasma treatment on the release kinetics of the drug Temozolomide (TMZ) from thin, biodegradable polyester films, comprising polylactic acid (PLA) and polyester urethane. The authors utilized two systems to achieve this, the first being diffuse coplanar surface barrier discharge, applying air as the gaseous medium, while the other involved capacitively coupled radio frequency discharge plasma under an argon atmosphere with hexamethyldisiloxane. Results showed that both forms of plasma treatment positively reduced the undesirable burst effect and benefited the release rate of TMZ. The hydrolytic degradability of the materials was slightly enhanced following hydrophilization, whereas the same diminished after hydrophobization had taken place. This was especially true for PLA due to modification of its wettability. © 2017 Taylor & Francis. | en |
utb.faculty | University Institute | |
dc.identifier.uri | http://hdl.handle.net/10563/1007673 | |
utb.identifier.obdid | 43879619 | |
utb.identifier.scopus | 2-s2.0-85029676535 | |
utb.identifier.wok | 000428134500004 | |
utb.identifier.coden | IJPMC | |
utb.source | j-scopus | |
dc.date.accessioned | 2018-01-15T16:31:38Z | |
dc.date.available | 2018-01-15T16:31:38Z | |
dc.description.sponsorship | 02/0199/14, VEGA, Vedecká Grantová Agentúra MŠVVaŠ SR a SAV; APVV-14-0518, APVV, Agentúra na Podporu Výskumu a Vývoja; QJ1310254, MZe, Ministerstvo Zemědělství; SAV, Slovenská Akadémia Vied; 15-08287Y, GACR, Grantová Agentura České Republiky; CZ.1.05/2.1.00/19.0409; LO1504 | |
dc.description.sponsorship | Czech Science Foundation [15-08287Y]; Ministry of Agriculture of the Czech Republic [QJ1310254]; Ministry of Education, Youth and Sports of the Czech Republic [LO1504, CZ.1.05/2.1.00/19.0409]; Ministry of Education, Science, Research and Sports of the Slovak Republic; Slovak Academy of Sciences, as a part of the "VEGA" project [02/0199/14]; Slovak Research and Development Agency [APVV-14-0518] | |
dc.rights.uri | https://authorservices.taylorandfrancis.com/publishing-open-access/oa-options-finder/ | |
utb.ou | Centre of Polymer Systems | |
utb.contributor.internalauthor | Stloukal, Petr | |
utb.contributor.internalauthor | Kucharczyk, Pavel | |
utb.contributor.internalauthor | Lehocký, Marián | |
utb.contributor.internalauthor | Sedlařík, Vladimír | |
utb.fulltext.affiliation | Petr Stloukal1,, Igor Novák2, Matej Mičušík2, Michal Procházka2, Pavel Kucharczyk1, Ivan Chodák2, Marian Lehocký1, Vladimír Sedlařík1 1 Centre of Polymer Systems, University Institute, Tomas Bata University in Zlín, tř. T. Bati, Zlín, Czech Republic, 2 Polymer Institute, Slovak Academy of Sciences, Dubravská cesta, Bratislava, Slovak Republic Corresponding author: Petr Stloukal, E-mail: StloukalP@seznam.cz | |
utb.fulltext.dates | Received 28 Dec 2016, Accepted 18 Mar 2017, Accepted author version posted online: 24 Apr 2017, Published online: 01 Dec 2017 | |
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utb.fulltext.sponsorship | This work was financially supported by the Czech Science Foundation (Grant No. 15-08287Y), the Ministry of Agriculture of the Czech Republic (Grant No. QJ1310254) and the Ministry of Education, Youth and Sports of the Czech Republic (GrantsNo. LO1504 and CZ.1.05/2.1.00/19.0409). The work was also supported by the Ministry of Education, Science, Research and Sports of the Slovak Republic and the Slovak Academy of Sciences, as part of the “VEGA” project (ref. 02/0199/14) and by the Slovak Research and Development Agency under contract No. APVV-14-0518 | |
utb.scopus.affiliation | Centre of Polymer Systems, University Institute, Tomas Bata University, Zlín, Czech Republic; Polymer Institute, Slovak Academy of Sciences, Bratislava, Slovakia | |
utb.fulltext.projects | 15-08287Y | |
utb.fulltext.projects | QJ1310254 | |
utb.fulltext.projects | LO1504 | |
utb.fulltext.projects | CZ.1.05/2.1.00/19.0409 | |
utb.fulltext.projects | VEGA 02/0199/14 | |
utb.fulltext.projects | APVV-14-0518 |