Slippery liquid-infused porous polymeric surfaces based on natural oil with antimicrobial effect

Habib, Salma; Zavahir, Sifani; Abusrafa, Aya E.; Abdulkareem, Asma; Sobolčiak, Patrik; Lehocký, Marián; Veselá, Daniela; Humpolíček, Petr; Popelka, Anton

dc.title	Slippery liquid-infused porous polymeric surfaces based on natural oil with antimicrobial effect	en
dc.contributor.author	Habib, Salma
dc.contributor.author	Zavahir, Sifani
dc.contributor.author	Abusrafa, Aya E.
dc.contributor.author	Abdulkareem, Asma
dc.contributor.author	Sobolčiak, Patrik
dc.contributor.author	Lehocký, Marián
dc.contributor.author	Veselá, Daniela
dc.contributor.author	Humpolíček, Petr
dc.contributor.author	Popelka, Anton
dc.relation.ispartof	Polymers
dc.identifier.issn	2073-4360 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued	2021
utb.relation.volume	13
utb.relation.issue	2
dc.citation.spage	1
dc.citation.epage	18
dc.type	article
dc.language.iso	en
dc.publisher	MDPI AG
dc.identifier.doi	10.3390/polym13020206
dc.relation.uri	https://www.mdpi.com/2073-4360/13/2/206
dc.subject	slippery surface	en
dc.subject	electrospinning	en
dc.subject	oil infusion	en
dc.subject	plasma treatment	en
dc.subject	antimicrobial activity	en
dc.description.abstract	Many polymer materials have found a wide variety of applications in biomedical indus-tries due to their excellent mechanical properties. However, the infections associated with the bio-film formation represent serious problems resulting from the initial bacterial attachment on the polymeric surface. The development of novel slippery liquid-infused porous surfaces (SLIPSs) repre-sents promising method for the biofilm formation prevention. These surfaces are characterized by specific microstructural roughness able to hold lubricants inside. The lubricants create a slippery layer for the repellence of various liquids, such as water and blood. In this study, effective antimi-crobial modifications of polyethylene (PE) and polyurethane (PU), as commonly used medical pol-ymers, were investigated. For this purpose, low-temperature plasma treatment was used initially for activation of the polymeric surface, thereby enhancing surface and adhesion properties. Subse-quently, preparation of porous microstructures was achieved by electrospinning technique using polydimethylsiloxane (PDMS) in combination with polyamide (PA). Finally, natural black seed oil (BSO) infiltrated the produced fiber mats acting as a lubricating layer. The optimized fiber mats’ production was achieved using PDMS/PA mixture at ratio 1:1:20 (g/g/mL) using isopropyl alcohol as solvent. The surface properties of produced slippery surfaces were analyzed by various microscopic and optics techniques to obtain information about wettability, sliding behavior and surface morphology/topography. The modified PE and PU substrates demonstrated slippery behavior of an impinged water droplet at a small tilting angle. Moreover, the antimicrobial effects of the produced SLIPs using black seed oil were proven against Gram-positive Staphylococcus aureus (S. au-reus) and Gram-negative Escherichia coli (E. coli). © 2021 by the authors. Licensee MDPI, Basel, Switzerland.	en
utb.faculty	University Institute
utb.faculty	Faculty of Technology
dc.identifier.uri	http://hdl.handle.net/10563/1010174
utb.identifier.obdid	43882447
utb.identifier.scopus	2-s2.0-85099150522
utb.identifier.wok	000611469300001
utb.source	j-scopus
dc.date.accessioned	2021-01-20T12:25:25Z
dc.date.available	2021-01-20T12:25:25Z
dc.description.sponsorship	Qatar National Research Fund ( Qatar Foundation) [JSREP07-022-3-010]; Qatar University [QUCG-CAM-20/21-3]; Ministry of Education, Youth and Sports of the Czech Republic DKRVO [RP/CPS/2020/001]
dc.description.sponsorship	Qatar National Research Fund, QNRF; Ministerstvo Školství, Mládeže a Tělovýchovy, MŠMT: RP/CPS/2020/001; Qatar University, QU: QUCG-CAM-20/21-3
dc.rights	Attribution 4.0 International
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/
dc.rights.access	openAccess
utb.ou	Centre of Polymer Systems
utb.contributor.internalauthor	Lehocký, Marián
utb.contributor.internalauthor	Veselá, Daniela
utb.contributor.internalauthor	Humpolíček, Petr
utb.fulltext.affiliation	Salma Habib 1 , Sifani Zavahir 1, Aya E. Abusrafa 1, Asma Abdulkareem 1, Patrik Sobolčiak 1, Marian Lehocky 2,3 , Daniela Vesela 2, Petr Humpolíček 2,3 and Anton Popelka 1,* 1 Center for Advanced Materials, Qatar University, Doha P.O. Box 2713, Qatar; salma.m.habib@hotmail.com (S.H.); fathima.z@qu.edu.qa (S.Z.); aya_abusrafa94@yahoo.com (A.E.A.); asma.alkareem@qu.edu.qa (A.A.); patrik@qu.edu.qa (P.S.) 2 Centre of Polymer Systems, Tomas Bata University in Zlin, Trida Tomase Bati 5678, 760 01 Zlin, Czech Republic; lehocky@post.cz (M.L.); dvesela@utb.cz (D.V.); humpolicek@utb.cz (P.H.) 3 Faculty of Technology, Tomas Bata University in Zlin, Vavreckova 275, 760 01 Zlin, Czech Republic * Correspondence: anton.popelka@qu.edu.qa; Tel.: +974-4403-5676
utb.fulltext.dates	Received: 9 November 2020 Accepted: 5 January 2021 Published: 8 January 2021
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utb.fulltext.sponsorship	This publication was made possible by Award JSREP07-022-3-010 from the Qatar National Research Fund (a member of The Qatar Foundation). This publication was supported by the Qatar University Collaborative grant number QUCG-CAM-20/21-3. The statements made herein are solely the responsibility of the authors. P.H., M.L. and D.V. acknowledge that this work was supported by the Ministry of Education, Youth and Sports of the Czech Republic DKRVO (RP/CPS/2020/001). XPS analysis was accomplished in part in the Gas Processing Center, College of Engineering, Qatar University. SEM analysis was accomplished in the Central Laboratories unit, Qatar University.
utb.wos.affiliation	[Habib, Salma; Zavahir, Sifani; Abusrafa, Aya E.; Abdulkareem, Asma; Sobolciak, Patrik; Popelka, Anton] Qatar Univ, Ctr Adv Mat, POB 2713, Doha, Qatar; [Lehocky, Marian; Vesela, Daniela; Humpolicek, Petr] Tomas Bata Univ Zlin, Ctr Polymer Syst, Trida Tomase Bati 5678, Zlin 76001, Czech Republic; [Lehocky, Marian; Humpolicek, Petr] Tomas Bata Univ Zlin, Fac Technol, Vavreckova 275, Zlin 76001, Czech Republic
utb.scopus.affiliation	Center for Advanced Materials, Qatar University, P.O. Box 2713, Doha, Qatar; Centre of Polymer Systems, Tomas Bata University in Zlin, Trida Tomase Bati 5678, Zlin, 760 01, Czech Republic; Faculty of Technology, Tomas Bata University in Zlin, Vavreckova 275, Zlin, 760 01, Czech Republic
utb.fulltext.projects	JSREP07-022-3-010
utb.fulltext.projects	QUCG-CAM-20/21-3
utb.fulltext.projects	RP/CPS/2020/001