Effect of strain on viscoelastic behavior of PVP-CMC based medicated hydrogels

Abstract

PVP-CMC and PVP-CMC-BA are designated as medicated hydrogels which are elastic in nature like other gels and solids. This present work was focused on the effect of strain on viscoelastic behavior of these medicated hydrogels. Dynamic frequency sweep test at 10% strain and dynamic strain sweep tests at different angular frequencies were performed on these hydrogels. Freshly prepared hydrogels and hydrogels swelled for 60 min from dry state were chosen for the experiments. These two experiments reveal that both PVP-CMC and PVP-CMC-BA hydrogels (fresh and swelled) maintain elastic behavior from very low to medium strain, but at high strain they become viscous in nature.